Bezzecchi wins by +17 over Martin
| Position | Rider | Bike | Points |
| 1 | Marco Bezzecchi | Aprilia | 173 |
| 2 | Jorge Martin | Aprilia | 156 |
| 3 | Fabio Di Giannantonio | Ducati | 134 |
| 4 | Pedro Acosta | KTM | 103 |
| 5 | Ai Ogura | Aprilia | 92 |
| 6 | Raul Fernandez | Aprilia | 88 |
| 7 | Francesco Bagnaia | Ducati | 82 |
| 8 | Marc Marquez | Ducati | 71 |
| 9 | Alex Marquez | Ducati | 67 |
| 10 | Fermin Aldeguer | Ducati | 58 |
| 11 | Luca Marini | Honda | 46 |
| 12 | Brad Binder | KTM | 42 |
| 12 | Enea Bastianini | KTM | 39 |
| 13 | Franco Morbidelli | Ducati | 38 |
| 15 | Fabio Quartararo | Yamaha | 37 |
| 16 | Johann Zarco | Honda | 34 |
| 17 | Diogo Moreira | Honda | 23 |
| 18 | Joan Mir | Honda | 15 |
| 19 | Alex Rins | Yamaha | 9 |
| 20 | Maverick Vinales | KTM | 5 |
| 21 | Augusto Fernandez | Yamaha | 4 |
| 22 | Toprak Razgatlioglu | Yamaha | 4 |
| 23 | Jack Miller | Yamaha | 3 |
| 24 | Jonas Folger | KTM | 0 |
| 25 | Michele Pirro | Ducati | 0 |
| 26 | Lorenzo Savadori | Aprilia | 0 |
| 27 | Cal Crutchlow | Honda | 0 |
Fourth win of the season for Marco Bezzecchi, the most important, because it comes at home at Mugello where he dominated ahead of his teammate Jorge Martin who dropped to -17.
Marc Marquez collected a nice 14 points this weekend, but is still now at -102 from the top of the standings.
Fabio Di Giannantonio continues to be consistent, but has slipped to -39 from Bezzecchi. Second consecutive podium for Francesco Bagnaia, Ai Ogura just missed completing the Aprilia hat-trick but has still returned ahead of teammate Raul Fernandez who made a mistake at the first braking point.
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A small point for Jack Miller who won the Yamaha cup, Diogo Moreira took the Honda cup ahead of Joan Mir and Luca Marini.
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